| 570 | Muhammad born in Mecca; |
| | Abbysinia, a Byzantine ally invades southern Arabia |
| 6th-7th Century | Byzantine Empire at war with Sassanian Persian Empire |
| 610 | Muhammad's revelations begin. |
| 622 | Migration of Muslims to Medina. |
| 632 | Muhammad dies; Abu Bakr becomes first Caliph. |
| 634-644 | Umar reigns as 2nd Caliph |
| 636 | Muslim armies defeat Byzantine and Persian armies. |
| 644-656 | Uthman is Caliph. Qur'an is compiled and standardized |
| 656 | Uthman murdered; Ali becomes Caliph |
| 661 | Ali is assassinated; Mu'awiya rules from Syria and founds Umayyad Dynasty (661-750). |
| 711 | Muslims invade Spain. |
| 732 | Charles Martel defeats Muslims in France. |
| 747 | Abbasid revolt begins. |
| 750 | Umayyads fall to Abbasid forces, remnant of family flees to Spain. |
| 755-1031 | Umayyads rule Spain. |
| 762 | Baghdad founded as Abbasid capital. |
| 786-809 | Reign of Harun al-Rashid. |
| 909-1171 | Shi'i dynasty rules Egypt & North Africa, Cairo founded. |
| 945-1055 | Buyids (a Shi'i family) control Baghdad & Iraq. |
| 1020 | Death of Firdawsi, Persian Epic poet, reviver of Persian Literature. |
| 1063-1157 | Seljuk Turks control Iraq. |
| 1097-1291 | Crusades. |
| 1171-1250 | Ayyubid Dynasty in Egypt. |
| 1250-1517 | Mamluk dynasty in Egypt. |
| 1271 | Marco Polo reaches Persia en route to China. |
| 1258 | Hulagu, Mongols sack Baghdad. |
| 1324-1360 | Ottoman family establishes and expands rule in Anatolia (Asia Minor). |
| 1369-1405 | Timur (Tamerlane) controls Persia and Mesopotamia. |
| 1425-30 | Ottoman-Venetian War |
| 1453 | Ottomans take Constantinople. |
| 1487 | Bartholomew Diaz rounds Cape of Good Hope. |
| 1499 | Isma'il establishes Safavid Dynasty in Iran; declares Shi'i belief and practice of Islam as official religious form for the Empire. |
| 1502 | Tabriz in Azerbaijan is made capital of Safavid Empire. |
| 1505 | Babur active in India establishing Moghul Dynasty. |
| 1514 | Shah Isma'il defeated by Ottomans; humiliated, he retires from public activity. |
| 1516 | Portugese take Hormuz. |
| 1517 | Ottomans defeat Mamluks, take Egypt and North Africa. |
| 1520-1556 | Reign of Suleyman the Magnificent as Ottoman Sultan. |
| 1600 | Shah Abbas makes Isfahan capital of Saffavid Empire. |
| 1664 | First major Ottoman defeat in Europe. |
| 1677-1681 | First Ottoman-Russian war. |
| 1722 | Afghans destroy Safavid power in Iran. |
| 1783 | Russia annexes Crimea, weakens Ottoman control of Black Sea. |
| 1798 | Napoleon takes Cairo. |
| 1805 | Muhammad Ali establishes rule in Egypt |
| 1821-1830 | Greek war of independence. |
| 1830 | French occupy Algeria |
| 1834 | First Arabic printing press established in Beirut. |
| 1844 | Sayyid Ali Muhammad declares himself to be The Bab. |
| 1866 | Syrian Protestant College established in Beirut, later becomes American University. |
| 1875 | British gain control of Egypt. |
| 1881 | French occupy Tunisia. | |
| | First Zionist mission to Palestine. Theodor Herzl begins revival of Hebrew as spoken language in Palestine. |
| 1882 | British quell Egyptian revolt. Lord Cromer installed as Consul General. |
| 1897 | First World Zionist Congress held in Basil, Switzerland; founds World Zionist Organization. |
| 1900-1908 | Hijaz railway built for Muslim pilgrims. |
| 1901 | Ibn Saud and the Wahhabis take Riyadh. |
| 1905-1908 | Constitutional Revolution in Iran. |
| 1912 | Agudat Yisrael founded as counterweight to World Zionist Organization |
| 1913 | Young Turk revolution takes over Ottoman government. |
| 1914 | Formation of al-Ahd, Arab Nationalist secret society. |
| 1914-1918 | World War I. |
| 1915 | Husayn-MacMahon correspondence begins, soliciting Arab support for Allied effort and promises British support for Arab state in Greater Syria. |
| 1916 | Sykes-Picot agreement between France and Great Britain for division of Ottoman lands. |
| 1917 | Balfour Declaration of British favor for Jewish state in Palestine. |
| 1919 | Turkish national congress meets. |
| 1920 | Faisal, son of Sherif Husayn of Mecca tries to establish Arab Rule in Damascus. |
| 1921 | Reza leads successful coup in Iran, establishes Pahlavi dynasty. |
| 1922 | League of Nations ratifies mandate system for European control of former Ottoman territories. |
| 1924 | Turkish republic established. |
| 1926 | Ibn Saud proclaimed King of Hijaz. |
| 1929 | Violent Arab resistance to British rule of Palestine Mandate. |
| 1936-7 | Arab revolt in Palestine. |
| 1938 (?) | Muslim Brotherhood formed in Egypt. |
| 1939 | Irgun members lead Jewish attacks on British holdings in Palestine. |
| 1939-1945 | World War II. |
| 1941 | Reza Shah of Iran deposed for German collaboration, son Muhammad installed. |
| 1945 | Arab League created. |
| 1947 | U.N. partition plan for Palestine approved. |
| 1948 | Isreal war of Independence. |
| 1951 | Mosaddeq elected Prime Minister of Iran. Nationalizes British Petroleum. |
| 1952 | Nasser leads Arab revolution in Egypt. |
| 1953 | Shah restored to power in Iran, Mosaddeq arrested |
| 1956 | Suez War. Egypt gains full control of canal and its revenues. |
| 1958 | Egypt and Syria form United Arab Republic. Dissolved in 1961. |
| 1963 | Ba'thist coup in Syria. Coup in Iraq. |
| 1963 | P.L.O formed. |
| 1967 | Arab-Israeli War. |
| 1968 | Coup in Iraq, consolidation of Ba'thist power. |
| 1969 | Yasser Arafat becomes head of PLO. |
| | Hafiz al-Asad takes control of Syrian government. |
| | Qaddafi leads revolt in Libya. |
| 1970 | Anwar Sadat succeedes Nasser as President of Egypt. |
| 1973 | Arab-Isaeli War. |
| 1975 | Iran-Iraq treaty to end border dispute. |
| 1978 | Camp David. |
| 1979 | Sadat assassinated in Egypt. Hosni Mubarak replaces Sadat and Prime Minister. |
| 1980 | Iran-Iraq war breaks out. |
| 1982 | Israel invades Lebanon. |
| 1987 | U.S. re-flags Kuwaiti oil tankers. |
| 1988 | Palestinian Intifada breaks out in Israeli Occupied Territories. |
| 1990 | (August) Iraq invades Kuwait and drives out ruling Sabah family. |
| 1991 | (January) U.S. led multi-national force attacks Iraqi forces in Kuwait and Iraq. Sabah family is restored to power in Kuwait. Iraq accepts U.N. terms of surrender. Saddam Hussein retains power |
| 1990-92 | Regional peace talks begin under U.S. and Soviet sponsorship to resolve disputes between Arab states, the Palestinians and Israel. |